Epithelial Barrier Theory

Key Publications


Yoo SKim JJeong ETHwang SJKang NGLee JPenetration rates into the stratum corneum layer: A novel quantitative indicator for assessing skin barrier functionSkin Res Technol202430:e13655. 

13 March 2024

Doyle ADMasuda MYPyon GC, et al. Detergent exposure induces epithelial barrier dysfunction and eosinophilic inflammation in the esophagusAllergy202378192201

28 July 2022

Rinaldi, AOLi, MBarletta, E, et al. Household laundry detergents disrupt barrier integrity and induce inflammation in mouse and human skinAllergy

27 September 2023

Saito K, Orimo K, Kubo T, et al. Laundry detergents and surfactants-induced eosinophilic airway inflammation by increasing IL-33 expression and activating ILC2s. Allergy.

10 May 2023

Schoenfelder H, Liu Y, Lunter DJ. Systematic investigation of factors, such as the impact of emulsifiers, which influence the measurement of skin barrier integrity by in-vitro trans-epidermal water loss (TEWL). Int J Pharm. 2023 May 10;638:122930. 

10 May 2023

Heichel TBrans RJohn SM, et al. Effects of impermeable and semipermeable glove materials on resolution of inflammation and epidermal barrier impairment after experimental skin irritationContact Dermatitis202389(1): 2636

04 April 2023

Masutani Y, Takai T, Kamijo S, et al. Skin Treatment with Detergent Induces Dermatitis with H1-Antihistamine-Refractory Itch and Upregulates IL-4 and Th17/Th22 Cytokine Gene Expression in C57BL/6 Mice. Int Arch Allergy Immunol. 2022;183(10):1040-1049. 

05 August 2022

Danby, S.G., Andrew, P.V., Kay, L.J., Pinnock, A., Chittock, J., Brown, K., Williams, S.F. and Cork, M.J. (2022), Enhancement of stratum corneum lipid structure improves skin barrier function and protects against irritation in adults with dry, eczema-prone skin. Br J Dermatol, 186: 875-886. 

18 December 2021

Ding W, Fan L, Tian Y, He C. Study of the protective effects of cosmetic ingredients on the skin barrier, based on the expression of barrier-related genes and cytokines. Mol Biol Rep. 2022 Feb;49(2):989-995. doi: 10.1007/s11033-021-06918-5.

19 November 2021

Morris SAV, Bobbitt JR, Ananthapadmanabhan KP, Kasting GB. The effect of prolonged exposure on sodium dodecyl sulfate penetration into human skin. Toxicol In Vitro. 2021 Dec;77:105246. 

December 2021

Vater C, Apanovic A, Riethmüller C, Litschauer B, Wolzt M, Valenta C, Klang V. Changes in Skin Barrier Function after Repeated Exposition to Phospholipid-Based Surfactants and Sodium Dodecyl Sulfate In Vivo and Corneocyte Surface Analysis by Atomic Force Microscopy. Pharmaceutics. 2021 Mar 24;13(4):436. 

24 March 2021

Schliemann, S., Müller, M., Stadeler, M. and Elsner, P. (2021), Double blind randomized repetitive efficacy test of various occupational skin protection preparations against sodium lauryl sulphate. JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 19: 545-552. 

25 March 2021

Muro Y, Ogawa-Momohara M, Takeichi T, Fukaya S, Yasuoka H, Kono M, Akiyama M. Clinical and serological features of dermatomyositis and systemic lupus erythematosus patients with autoantibodies to ADAR1. J Dermatol Sci. 2020 Oct;100(1):82-84. 

18 August 2020