Public Information

Redefining toxicity to reimagine “clean” is an important concept, especially in the context of environmental sustainability, public health, and the products we use in our daily lives.

Epithelial barrier theory and the changing concept of chronic microtoxicity.

Here is a list of epithelial barrier damaging substances with data developed from our labs. Air pollutants, household chemicals, food additives, microplastics, nanoparticles.

How to reduce exposure to epithelial barrier-damaging agents in homes

The Epithelial Barrier Theory is a comprehensive explanation for the global, epidemic-level rise in chronic health conditions over the past 65 years. The theory, postulated by Akdis, proposes that exposure to toxic substances introduced by industrialization and modern lifestyle changes disrupts the epithelial barrier of the skin, upper and lower airways, and gut mucosa and causes microbial dysbiosis triggering an inflammatory immune response that can initiate or aggravate many chronic inflammatory diseases.